Bayesian Gaussian Mixture Models for High-Density Genotyping Arrays
نویسندگان
چکیده
منابع مشابه
Bayesian Gaussian Mixture Models for High-Density Genotyping Arrays.
Affymetrix's SNP (single-nucleotide polymorphism) genotyping chips have increased the scope and decreased the cost of gene-mapping studies. Because each SNP is queried by multiple DNA probes, the chips present interesting challenges in genotype calling. Traditional clustering methods distinguish the three genotypes of an SNP fairly well given a large enough sample of unrelated individuals or a ...
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ژورنال
عنوان ژورنال: Journal of the American Statistical Association
سال: 2008
ISSN: 0162-1459,1537-274X
DOI: 10.1198/016214507000000338